DNA Viruses

DNA Viruses

A Practical Approach

eBook - 2000
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Book News
Describes in detail major experimental methods for studying DNA viruses, from fundamentals of virus culture to novel techniques such as surface plasmon resonance spectrometry and real-time PCR analysis of drug resistance mutations. Describes the culture of DNA viruses and the extraction, purification, and characterization of virus DNA, then discusses aspects of virus genome mapping, correlation of genotype with phenotype, sequence analysis, mutagenesis of DNA virus genomes, and identification and study of trans-acting regulatory proteins. Cann teaches in the department of microbiology and immunology at the University of Leicester. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Oxford University Press
DNA Viruses: A Practical Approach groups together the major experimental methods currently employed to study DNA viruses, from the fundamentals of virus culture to novel techniques such as surface plasmon resonance spectrometry and realtime PCR analysis of drug resistance mutations in clinical isolates. Chapter 1 provides an overview of the extraction, purification and characterizations of virus DNA, but also covers the fundamentals of DNA virus culture. Chapters 2 and 3 describe approaches to the molecular investigation and mutagenesis of DNA virus genomes. Chapter 4 considers DNA virus replication and then chapters 5 & 6 describe methods to study transcription control. Chapters 7 to 9 consider aspects of the pathogenesis of DNA virus infections. The final chapter describes the current technology being applied to the development of DNA virus vectors for gene delivery. This volume will therefore be of interest to all those working on DNA viruses whether in academia, industry or clinical research.

Publisher: Oxford : New York : Oxford University Press, 2000
ISBN: 9780585484112
Characteristics: 1 online resource (xx, 314 pages) : illustrations
Additional Contributors: Cann, Alan


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